Liposomal

Liposomes are advanced nano-scale delivery systems composed of phospholipid bilayers that mimic biological membrane structures. These spherical vesicles (typically 50-500 nm in diameter) enable:

1. Enhanced Bioavailability

   • Encapsulate hydrophilic (aqueous core) & hydrophobic (lipid layer) compounds

   • Increase drug solubility up to 1000-fold compared to free molecules

2. Targeted Delivery

   • Surface-modifiable with ligands (e.g., folic acid, antibodies) for cell-specific targeting

   • Achieve 3-5x higher tumor accumulation via EPR (Enhanced Permeability & Retention) effect

3. Stability Optimization

   • PEGylation extends circulation half-life from 2h to 24h+

   • Lyophilization enables 2-year shelf life at 4°C

4. Cross-Industry Applications

   • Pharma: siRNA delivery, cancer therapeutics (Doxil®)

   • Cosmeceuticals: Vitamin C/Retinol stabilization (pH 5.5-7.0 compatibility)

   • Nutraceuticals: Probiotic encapsulation (85% survival rate through GI tract)